Ancestry painting with local ancestry inference

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The 23Andme, Inc. patent solves the following problem:

Ancestry deconvolution aims to recognize the ancestral origin of chromosomal people. Ancestry deconvolution admixed individuals (ie, those whose ancestors as grandparents from different regions) is straightforward when the global population considered sufficient (for example, a grandfather from Europe and one from Asia). To date, however, current methods are often not effective in distinguishing between closely related populations (eg, in Europe). Furthermore, because of their computational complexity, the current procedures for background deconvolution not good for application in setting large-scale, which references ornaments used include thousands of people.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9367800 B1 deals with Ancestry painting with local ancestry inference.
Presenting ancestral origin of information, comprising: receiving a request to display genealogical data to an individual; obtaining background information on composition of each, the ethnic composition information including information about a number of genotype data of individuals, considered to be equivalent to a specific origin; and presenting the ancestors composition information shown.

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Trio-based phasing using a dynamic Bayesian network

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The 23Andme, Inc. patent solves the following problem:

Ancestry deconvolution aims to recognize the ancestral origin of chromosomal people. Ancestry deconvolution admixed individuals (ie, those whose ancestors as grandparents from different regions) is straightforward when the global population considered sufficient (for example, a grandfather from Europe and one from Asia). To date, however, current methods are often not effective in distinguishing between closely related populations (eg, in Europe). Furthermore, because of their computational complexity, the current procedures for background deconvolution not good for application in setting large-scale, which references ornaments used include thousands of people.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9213944 B1 deals with Trio-based phasing using a dynamic Bayesian network.
Do three-based elimination include: earn a set of preliminary data on haplotype a man; build a dynamic Bayesian network based at least in part on the preliminary set of haplotype data on individuals and on the haplotype data with at least one parent of the individual; and determine, based on dynamic Bayesian network, a set of refined haplotype data individually.

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Summarizing an aggregate contribution to a characteristic for an individual

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The 23Andme, Inc. patent solves the following problem:

Recently, interest in genetics and genetic testing raised as to increase the amount of research on how genetic information of a human influence on a person's background, appearance, behavior, and physiology. Genetic testing can provide information to help people understand the areas of potential concern to discuss with their doctors, and with a doctor, help individuals to make decisions about medical management and life-style choices. Typical genetic testing solutions allow a person to order a particular genetic test, such as type 2 diabetes. individual usually receives a summary report with a limited set of results with limited interpretative information. Progress interpretation and reporting of genetic test results useful.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 8510057 B1 deals with Summarizing an aggregate contribution to a characteristic for an individual.
Summarized in an aggregate contribution to a characteristic of individual states, including to determine the nature of evaluating, identifying one or more points associated with nature, to recover measure the individual for each of the one or more points out of a database of individuals' points, taking a statistical thing to measure the association between the signs associated with nature and characteristics for each with one or more points from the database sign, and to determine the aggregate contributions based at least in part on the acquired statistical reasons.

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Polymorphisms associated with Parkinson’s disease

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The 23Andme, Inc. patent solves the following problem:

Parkinson's disease (PD) is a progressive degenerative disease of the central nervous system (CNS). PD is characterized by muscle rigidity, tremor, a slow physical movement (bradykinesia), impaired balance and coordination, and, in advanced stages, a loss of physical movement (akinesia). Over one million Americans suffer from Parkinson's disease, with prevalence of approximately 1 in 272 or 0.37% in the United States (US Census Bureau, Population Estimates, 2004).

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 8187811 B2 deals with Polymorphisms associated with Parkinson’s disease.
invention provides human polymorphisms associated with Parkinson's disease (PD). Also disclosed are compositions and methods for use in diagnostics, prognostics, prevention, treatment and / or study in PD.

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