Trio-based phasing using a dynamic Bayesian network

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The 23Andme, Inc. patent solves the following problem:

Ancestry deconvolution aims to recognize the ancestral origin of chromosomal people. Ancestry deconvolution admixed individuals (ie, those whose ancestors as grandparents from different regions) is straightforward when the global population considered sufficient (for example, a grandfather from Europe and one from Asia). To date, however, current methods are often not effective in distinguishing between closely related populations (eg, in Europe). Furthermore, because of their computational complexity, the current procedures for background deconvolution not good for application in setting large-scale, which references ornaments used include thousands of people.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9213944 B1 deals with Trio-based phasing using a dynamic Bayesian network.
Do three-based elimination include: earn a set of preliminary data on haplotype a man; build a dynamic Bayesian network based at least in part on the preliminary set of haplotype data on individuals and on the haplotype data with at least one parent of the individual; and determine, based on dynamic Bayesian network, a set of refined haplotype data individually.

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Cohort selection with privacy protection

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The 23Andme, Inc. patent solves the following problem:

Now, clinical target specific genetic factors in human subjects research is often made to attract candidates who have a certain genetic condition through special pools (eg, patient groups), screening for particular genotypes studied, and the selection of members based on screening results. The selection process tends to be difficult for several reasons. First, a large number of candidates often need to recruit. To help these people, to make them interested in studying, and getting them to sign on to be expensive and time consuming. Second, all the candidates have to be screened to determine if they have a specific genetic condition, which is an expensive and laborious process. For study of rare genetic conditions in particular, many iterations will be needed to achieve a significant population study.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 8990250 B1 deals with Cohort selection with privacy protection.
Assembling a band include: receiving the genetic nature of information concerning a desired genetic traits; the use of genetic traits to seek information in a data store containing information previously genotyped individuals to take a group of candidates with the desired genetic traits; and gathering battalion based at least in part the group of candidates.

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De-identification and sharing of genetic data

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The 23Andme, Inc. patent solves the following problem:

Recently, interest in genetics and genetic testing raised as to increase the amount of research on how genetic information of a human influence on a person's background, appearance, behavior, and physiology. Genetic information may be available to a person through the Internet. To prevent others from seeing the personal data, the individual is often required to login using a password to gain access to his data. In some cases, a person may want to share his personal information with one or more other people, such as family members. However, current techniques for sharing personal data on basic and had limited capabilities. Moreover, current techniques can be vulnerable to attack, possibly allowing personal data to be compromised. Thus, growth in the share of personal data that can be useful.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 8589437 B1 deals with De-identification and sharing of genetic data.
A system for separate recognition of data from personal data exposed. system includes: a first set of stored data comprising a plurality of recognition data structures containing identifying data; a second set of stored data comprising a plurality of personal data structures containing personal data; a set of mapping data comprising a plurality of records, where each mapping is in the midst of a recognition framework data and a personal data structure; and an application configured to receive data mapping associated with a mapping, determine a mapping associated with the mapping data, and gain a personal structure that data base mapping. The set of data mapping is logically separate from the first set of stored data, the second set of stored data, and applications.

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Genotype calling

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The 23Andme, Inc. patent solves the following problem:

The instructions for making cells in the human body is encoded in deoxyribonucleic acid (DNA). DNA is a long, ladder-shaped molecule, each equivalent to climb up on a pair of interlocking units, called bases, appointed by the four letters of DNA AlphaBeta, T, G and C. a always pairs or chains with T, and G always pairs or chains with C. the order of these four letters in one DNA called human genome.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 8428886 B2 deals with Genotype calling.
Determine a genetic sequence for a particular place in the genome of a man declared, including: receiving a measure associated with a particular file for the particular on the human genome, to receive contextual information associated with a context of individual within a larger collection of genetic information, and the use of measures associated with particular order -is and contextual information to calculate an improved determination of genetic sequences to particular parts of the human genome.

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