Cohort selection with privacy protection

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The 23Andme, Inc. patent solves the following problem:

Now, clinical target specific genetic factors in human subjects research is often made to attract candidates who have a certain genetic condition through special pools (eg, patient groups), screening for particular genotypes studied, and the selection of members based on screening results. The selection process tends to be difficult for several reasons. First, a large number of candidates often need to recruit. To help these people, to make them interested in studying, and getting them to sign on to be expensive and time consuming. Second, all the candidates have to be screened to determine if they have a specific genetic condition, which is an expensive and laborious process. For study of rare genetic conditions in particular, many iterations will be needed to achieve a significant population study.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9405818 B2 deals with Cohort selection with privacy protection.
Assembling a band include: receiving the genetic nature of information concerning a desired genetic traits; the use of genetic traits to seek information in a data store containing information previously genotyped individuals to take a group of candidates with the desired genetic traits; and gathering battalion based at least in part the group of candidates.

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Ancestry painting with local ancestry inference

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The 23Andme, Inc. patent solves the following problem:

Ancestry deconvolution aims to recognize the ancestral origin of chromosomal people. Ancestry deconvolution admixed individuals (ie, those whose ancestors as grandparents from different regions) is straightforward when the global population considered sufficient (for example, a grandfather from Europe and one from Asia). To date, however, current methods are often not effective in distinguishing between closely related populations (eg, in Europe). Furthermore, because of their computational complexity, the current procedures for background deconvolution not good for application in setting large-scale, which references ornaments used include thousands of people.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9367800 B1 deals with Ancestry painting with local ancestry inference.
Presenting ancestral origin of information, comprising: receiving a request to display genealogical data to an individual; obtaining background information on composition of each, the ethnic composition information including information about a number of genotype data of individuals, considered to be equivalent to a specific origin; and presenting the ancestors composition information shown.

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Genome sharing

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The 23Andme, Inc. patent solves the following problem:

Recently, interest in genetics and genetic testing raised as to increase the amount of research on how genetic information of a human influence on a person's background, appearance, behavior, and physiology. Genetic information may be available to a person through the Internet. To prevent others from seeing the personal data, the individual is often required to login using a password to gain access to his data. In some cases, a person may want to share his personal information with one or more other people, such as family members. However, current techniques for sharing personal data on basic and had limited capabilities. Thus, growth in the share of personal data that can be useful.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9336177 B2 deals with Genome sharing.
Sharing the data revealed. In some cases, the sharing of data includes receiving a request to share information from a first account to a second account, receiving an indication of a plurality of first profile account associated with the first account to share with the second account, and build share from the plurality of first account profile in the second account, which divide up the second account with read access to a subset of nonpublic data associated with the plurality of first profile accounts.

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Processing data from genotyping chips

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The 23Andme, Inc. patent solves the following problem:

The instructions for making cells in the human body is encoded in deoxyribonucleic acid (DNA). DNA is a long, ladder-shaped molecule, each equivalent to climb up on a pair of interlocking units, called bases, appointed by the four letters of DNA AlphaBeta, T, G and C. a always pairs or chains with T, and G always pairs or chains with C. the order of these four letters in one DNA called human genome.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9218451 B2 deals with Processing data from genotyping chips.
Processing genetic data includes receiving two or more sets of genetic data for an individual from one or more genetic source of data, where the genetic data set contains the data of deoxyribonucleic acid individuals (DNA); combining the genetic data sets from one or more genetic data sources to obtain a set of merged genetic data for each, including: identifying genetic data sets of data contradictory, acknowledged that data corresponding to a genetic marker associated with a difference that takes place in a region of the human genome; analyzing the identified data to resolve a dispute dedicated to recognizing conflicting data and automatically determine a proper value corresponding to the genetic mark, the analysis and the determination based at least part of the contextual information; and gather the appropriate value of the set of merged genetic data.

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Trio-based phasing using a dynamic Bayesian network

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The 23Andme, Inc. patent solves the following problem:

Ancestry deconvolution aims to recognize the ancestral origin of chromosomal people. Ancestry deconvolution admixed individuals (ie, those whose ancestors as grandparents from different regions) is straightforward when the global population considered sufficient (for example, a grandfather from Europe and one from Asia). To date, however, current methods are often not effective in distinguishing between closely related populations (eg, in Europe). Furthermore, because of their computational complexity, the current procedures for background deconvolution not good for application in setting large-scale, which references ornaments used include thousands of people.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9213944 B1 deals with Trio-based phasing using a dynamic Bayesian network.
Do three-based elimination include: earn a set of preliminary data on haplotype a man; build a dynamic Bayesian network based at least in part on the preliminary set of haplotype data on individuals and on the haplotype data with at least one parent of the individual; and determine, based on dynamic Bayesian network, a set of refined haplotype data individually.

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Scalable pipeline for local ancestry inference

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The 23Andme, Inc. patent solves the following problem:

Ancestry deconvolution aims to recognize the ancestral origin of chromosomal people. Ancestry deconvolution admixed individuals (ie, those whose ancestors as grandparents from different regions) is straightforward when the global population considered sufficient (for example, a grandfather from Europe and one from Asia). To date, however, current methods are often not effective in distinguishing between closely related populations (eg, in Europe). Furthermore, because of their computational complexity, the current procedures for background deconvolution not good for application in setting large-scale, which references ornaments used include thousands of people.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9213947 B1 deals with Scalable pipeline for local ancestry inference.
Ancestry deconvolution includes gain unphased genotype data in an individual; destroy, to use one or more processors, unphased genotype data creation of haplotype data; Using a machine learning to classify the portion of lost data haplotype as equivalent in certain ancestries individuals and create initial classification results; and correction of errors in the classification results in the creation of modified classification results.

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Specimen sample collection system

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The Oasis Diagnostics, Corporation patent solves the following problem:

Over the last few years there was a large increase in area of ​​salivary diagnostics, prompted in part by efforts from the National Institutes of Health (NIH) and the National Institute of Dental and Craniofacial Research (NIDCR) division to improve development of non-invasive technology for the diagnosis of disease and to measure specific analytes or molecules in saliva or oral fluid sample. These agencies make funds available for the development of novel, innovative tools including microarrays, lab-on-a-chip, lateral flow, ELISA and other technologies to use saliva and other non- invasive sampling method. Some reasons for the increased interest in salivary diagnostics involves the development of important new technologies for the collection and testing of oral fluids and improvements in the manufacturability of such devices.

Our analysis of this patent is as follows:

Oasis Diagnostics, Corporation’s patent US 9198641 B2 deals with Specimen sample collection system.
A specimen sample collection system includes a handle having opposed first and second ends, and a sufficient sign with the shaft, wherein the second end management and sufficiency indicator of a hole adapted to receive a sample collection pad; a sample collection pad with opposing ends, the sample collection pad partially within and extending from the direction of the second end, and in contact with enough evidence, the sample collection pad with a cylindrical cross section; and, in a pad compression tube having a first open end to go over the sample collection pad and the second end of the handle, an opposing second end, an inner surface extending therebetween, and at least outlet port proximal to the pad compression tube second end and in fluid communication with the pad compression tube inside. The system may include where sufficient evidence is a light pipe, or other elements that showed, providing visual, aural or haptic indication of sufficient sample volume. The system may include where sufficient evidence includes longitudinal channel extending along the inner surface in contact with the sample collection pad to provide a way for displacement air. The system may include a sealing member to seal against a pad compression tube and perform specimen collection pad. The system may include one or more collection tubes attachable to one or more of the pad compression tube outlet port. The system may include ergonomic portion of the rod and pad compression tube. The system may include a specimen collection pad with a whole cross section of a reduced cross section portion, including a shoulder making a sealing member and an angled face to conform to the inner surface of a light pipe sufficiency indicator. The system may include one or more in-line filter next to the pad compression tube outlet port. The system may include additional features as described herein.

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Identification of matrilineal or patrilineal relatives

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The 23Andme, Inc. patent solves the following problem:

Genealogy is the study of family history and lineage of ancestors. It is an interesting subject to study many professionals as well as hobbyists. Traditional techniques genealogical study often includes building family trees based on surnames and historical records. As gene sequencing technology becomes more accessible, there is growing interest in genetic ancestry testing in recent years.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 9116882 B1 deals with Identification of matrilineal or patrilineal relatives.
Determine relative relationships among a mass of people, namely: access to user-specified genealogical information at least some of the plurality of individuals and genetic information recombinable deoxyribonucleic acid (DNAs ) at least some of the plurality of individuals; determining, using one or more computer processors and among the mass of people, one or more related people relative to a target individual, and information concerning one or more more related individuals, and present information about at least one of the one or more related individuals, including the presentation of a sign in if at least one of one or more related to individuals is a matrilineal relative or a patrilineal relative to each target.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Cohort selection with privacy protection

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The 23Andme, Inc. patent solves the following problem:

Now, clinical target specific genetic factors in human subjects research is often made to attract candidates who have a certain genetic condition through special pools (eg, patient groups), screening for particular genotypes studied, and the selection of members based on screening results. The selection process tends to be difficult for several reasons. First, a large number of candidates often need to recruit. To help these people, to make them interested in studying, and getting them to sign on to be expensive and time consuming. Second, all the candidates have to be screened to determine if they have a specific genetic condition, which is an expensive and laborious process. For study of rare genetic conditions in particular, many iterations will be needed to achieve a significant population study.

Our analysis of this patent is as follows:

23Andme, Inc.’s patent US 8990250 B1 deals with Cohort selection with privacy protection.
Assembling a band include: receiving the genetic nature of information concerning a desired genetic traits; the use of genetic traits to seek information in a data store containing information previously genotyped individuals to take a group of candidates with the desired genetic traits; and gathering battalion based at least in part the group of candidates.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Automated system for the comparison of individual genome, transcriptome, proteome, epigenome, and metabolome data with data from bonemarrow donor registers and blood banks, umbilical cord blood banks and tissue banks

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The Cytolon Ag patent solves the following problem:

Our analysis of this patent is as follows:

Cytolon Ag’s patent US 8788214 B2 deals with Automated system for the comparison of individual genome, transcriptome, proteome, epigenome, and metabolome data with data from bonemarrow donor registers and blood banks, umbilical cord blood banks and tissue banks.
The invention relates to a system for the automatic, rapid and dynamic allocation of biological cells for transplantation, therapy, or research purposes between the central bank or collection (storage) and hospitals, transplant center or research facilities, and to monitor and support the process of transmission to request delivery of a cell preparation suitable for allogeneic transplantation, through the use of budget preparation in tracking the results to patients and to provide these data for statistical and other purposes, as well as providing molecular diagnostic results in individuals with the aim to determine optionseven advanceof transplantations among the inventory register or banks. Using the said system, it is possible that the first road timeeven and online and with automatic retriesto offer complete solutions in the form of transplantations specific and individual cases.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.